Chronobiology, excessive daytime sleepiness and depression: Is there a link?
نویسندگان
چکیده
The complaint of excessive daytime sleepiness (EDS), commonly encountered in clinical practice, may arise from a variety of psychiatric disorders, most importantly depression. Even though EDS frequently leads depressed patients to seek medical assistance, it is commonly under-evaluated and under-diagnosed. Therefore, a comprehensive understanding and management of EDS is essential in the clinical assessment of depression. Within a theoretical framework, a chronobiological approach may shed new light on the complex interaction of EDS and depression. In this review, studies on EDS and depression are summarized and discussed within the context of circadian and sleep regulatory mechanisms. Furthermore, potential chronobiological therapeutic strategies are proposed to address some of the unmet needs in the treatment of EDS and depression.
منابع مشابه
ارزیابی یافتههای پلی سومنوگرافی در بیماران مبتلا به آپنه انسدادی حین خواب با و بدون خواب آلودگی طی روز
Introduction: Obstructive sleep apnea syndrome(OSAS) is a common disorder in the general population. Excessive daytime sleepiness (EDS) is a frequent symptom in patients with OSA. Obstructive sleep apnea and its resultant EDS lead to an increased risk of deadly motor vehicle accidents. In this study the relationship between EDS and different polysomnographic variables in patients sufferinf from...
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Background: Sleepiness that occurs at inappropriate or undesirable times or that interferes with daytime activities is generally considered excessive daytime sleepiness. Obstructive Sleep Apnea (OSA) is one of the most common causes of excessive daytime sleepiness. The aim of this study is to finds out the most important nocturnal polysomnographic parameters influencing daytime sleepiness in pa...
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ورودعنوان ژورنال:
- Sleep medicine
دوره 10 5 شماره
صفحات -
تاریخ انتشار 2009